2. Metabolic Disease

Metabolic Disease

Metabolic Disease

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Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W012999R
    Tiglic acid (Standard) 80-59-1 98%
    Tiglic acid (Standard) is the analytical standard of Tiglic acid (HY-W012999). This product is intended for research and analytical applications. Tiglic acid is a monocarboxylic unsaturated organic acid. Tiglic acid can be isolated from croton oil. Tiglic acid agonizes FFA2 and upregulates PYY expression. Tiglic acid derivatives have anti-inflammatory activity. Tiglic acid can be used in the research of obesity, diabetes, and inflammatory diseases.
    Tiglic acid (Standard)
  • HY-W013014R
    3-Methyl-2-cyclopenten-1-one (Standard) 2758-18-1
    3-Methyl-2-cyclopenten-1-one (Standard) is the analytical standard of 3-Methyl-2-cyclopenten-1-one. This product is intended for research and analytical applications. 3-Methyl-2-cyclopenten-1-one is an endogenous metabolite.
    3-Methyl-2-cyclopenten-1-one (Standard)
  • HY-W013035R
    3-Methyl-2-buten-1-ol (Standard) 556-82-1 98%
    3-Methyl-2-buten-1-ol (Standard) is the analytical standard of 3-Methyl-2-buten-1-ol. This product is intended for research and analytical applications. 3-Methyl-2-buten-1-ol (MBO321) is an orally active endogenous metabolite found in pine trees and is used as a fragrance ingredient in cosmetics and detergents. 3-Methyl-2-buten-1-ol passes cell barrier. 3-Methyl-2-buten-1-ol reduces body weight in rats[1][2][3].
    3-Methyl-2-buten-1-ol (Standard)
  • HY-W013049R
    Docosanoic acid (Standard) 112-85-6 98%
    Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans.
    Docosanoic acid (Standard)
  • HY-W013061R
    Propane-1,2,3-triyl tripalmitate (Standard) 555-44-2
    Propane-1,2,3-triyl tripalmitate (Standard) is the analytical standard of Propane-1,2,3-triyl tripalmitate (HY-W013061). This product is intended for research and analytical applications. Propane-1,2,3-triyl tripalmitate is a saturated fat. Propane-1,2,3-triyl tripalmitate enhances the lymphatic transport of Glycerol tristearate (HY-127035).
    Propane-1,2,3-triyl tripalmitate (Standard)
  • HY-W013061S
    Propane-1,2,3-triyl tripalmitate-d9 2738376-70-8 98%
    Propane-1,2,3-triyl tripalmitate-d9 is deuterium labeled Propane-1,2,3-triyl tripalmitate (HY-W013061). Propane-1,2,3-triyl tripalmitate is a saturated fat. Propane-1,2,3-triyl tripalmitate enhances the lymphatic transport of Glycerol tristearate (HY-127035).
    Propane-1,2,3-triyl tripalmitate-d9
  • HY-W013063S
    1,2-Dilinoleoyl-sn-glycero-3-phosphocholine-d11 98%
    1,2-Dilinoleoyl-sn-glycero-3-phosphocholine-d11 is a deuterium labeled 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine (HY-W013063). 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine is a phospholipid. 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine can be used for obesity research.
    1,2-Dilinoleoyl-sn-glycero-3-phosphocholine-d11
  • HY-W013078R
    (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate (Standard) 998-07-2
    (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate (Standard) is the analytical standard of (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate. This product is intended for research and analytical applications. (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate is an endogenous metabolite.
    (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate (Standard)
  • HY-W013078S
    (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate-d54 326495-41-4 99.0%
    (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate-d54 is deuterium labeled (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate. (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl
    (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate-d54
  • HY-W013175R
    Uridine 5'-monophosphate disodium salt (Standard) 3387-36-8 98%
    Uridine 5'-monophosphate (disodium salt) (Standard) is the analytical standard of Uridine 5'-monophosphate (disodium salt). This product is intended for research and analytical applications. Uridine 5'-monophosphate (5'-Uridylic acid) disodium salt is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate disodium salt can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea.
    Uridine 5'-monophosphate disodium salt (Standard)
  • HY-W013179S
    18-Hydroxycorticosterone-d4 1257742-38-3 98%
    18-Hydroxycorticosterone-d4 is the deuterium labeled 18-Hydroxycorticosterone. 18-Hydroxycorticosterone is a corticosteroid and a derivative of corticosterone, which can lead to serious electrolyte imbalances.
    18-Hydroxycorticosterone-d4
  • HY-W013266R
    N4-Acetylsulfamethoxazole (Standard) 21312-10-7
    N4-Acetylsulfamethoxazole (Acetylsulfamethoxazole) Standard of N4-Acetylsulfamethoxazole (HY-W013266). This product is intended for research and analytical applications. N4-Acetylsulfamethoxazole (Acetylsulfamethoxazole) is the N4-acetylated metabolite of Sulfamethoxazole (HY-B0322).
    N4-Acetylsulfamethoxazole (Standard)
  • HY-W013573R
    S-Allyl-L-cysteine (Standard) 21593-77-1
    S-Allyl-L-cysteine (Standard) is the analytical standard of S-Allyl-L-cysteine. This product is intended for research and analytical applications. S-Allyl-L-cysteine, one of the organosulfur compounds found in AGE, possess various biological effects including neurotrophic activity, anti-cancer activity, anti-inflammatory activity.
    S-Allyl-L-cysteine (Standard)
  • HY-W014125R
    Undecanedioic acid (Standard) 1852-04-6
    Undecanedioic acid (Standard) is the analytical standard of Undecanedioic acid (HY-W014125). Undecanedioic acid is an oral activie nndogenous metabolite. Undecanedioic acid is associated with intercellular matrix macromolecules and specifically with elastin.
    Undecanedioic acid (Standard)
  • HY-W014125S
    Undecanedioic acid-d18 98%
    Undecanedioic acid-d18 is the deuterium labeled Undecanedioic acid (HY-W014125). Undecanedioic acid is an oral activie nndogenous metabolite. Undecanedioic acid is associated with intercellular matrix macromolecules and specifically with elastin.
    Undecanedioic acid-d18
  • HY-W014130A
    N-Acetyl-L-arginine dihydrate 210545-23-6 98%
    N-Acetyl-L-arginine (Ac-Arg-OH) dihydrate is an endogenous metabolite.
    N-Acetyl-L-arginine dihydrate
  • HY-W014410R
    Mucic acid (Standard) 526-99-8 98%
    Mucic acid (Standard) is the analytical standard of Mucic acid (HY-W014410). This product is intended for research and analytical applications. Mucic acid is an aldonic acid that can be prepared from pectin. Mucic acid increases the expression level of Runx2, promotes osteoblast differentiation, and upregulates osteogenic differentiation marker genes. Mucic acid can be used to prepare platform compounds, polymers, polymer materials and metal-organic frameworks. Mucic acid is applicable to the research of bone-related defects.
    Mucic acid (Standard)
  • HY-W014787R
    Decanedioic acid (Standard) 111-20-6 98%
    Decanedioic acid (Standard) is the analytical standard of Decanedioic acid (HY-W014787). This product is intended for research and analytical applications. Decanedioic acid is a straight-chain dicarboxylic acid. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetes. Decanedioic acid prevents and reverses metabolic-associated liver disease and obesity. Decanedioic acid is associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency.
    Decanedioic acid (Standard)
  • HY-W015213S
    Adenine monohydrochloride hemihydrate-15N5 98%
    Adenine monohydrochloride hemihydrate-15N5 is the 15N labeled Adenine monohydrochloride hemihydrate (HY-W015213). Adenine monohydrochloride hemihydrate is a hydrochloride derivative of Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
    Adenine monohydrochloride hemihydrate-15N5
  • HY-W015224R
    Methyl 2-(1H-indol-3-yl)acetate (Standard) 1912-33-0 98%
    Methyl 2-(1H-indol-3-yl)acetate (Standard) is the analytical standard of Methyl 2-(1H-indol-3-yl)acetate. This product is intended for research and analytical applications. Methyl 2-(1H-indol-3-yl)acetate is an endogenous metabolite.
    Methyl 2-(1H-indol-3-yl)acetate (Standard)
Cat. No. Product Name / Synonyms Application Reactivity